ESH AL 2018 | Managing AML in elderly patients

Christoph Röllig

Traditionally, the standard therapy for the management of acute myeloid leukemia (AML) in elderly patients has been low-dose cytarabine, but hypomethylating agents (HMAs) have quickly become the backbone of AML treatment in many countries. Here, Christoph Röllig, MD, from the University Hospital Carl Gustav Carus, Dresden, Germany, provides evidence for the efficacy of HMAs in the elderly and those with unfavorable cytogenetics, including an increased tolerability and decreased toxicity when compared to intensive chemotherapy. Early clinical trials into HMAs combined with other drugs, such as venetoclax, have demonstrated increased complete remission rates and prolonged survival in elderly AML patients. This interview was recorded at the 2018 European School of Hematology (ESH) Clinical Updates on Acute Leukemias, held in Budapest, Hungary.

Share this video  

Sign-up for our Newsletter!

Keep up to date with all the latest news with our monthly newsletter