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EHA 2023 | IMerge update: continuous transfusion independence & disease modification with imetelstat in LR-MDS

Amer Zeidan, MBBS, Yale University, New Haven, CT, shares the results of the Phase III IMerge study (NCT02598661) evaluating imetelstat in patients with lower-risk myelodysplastic syndromes (MDS). The trial reported promising results in terms of transfusion independence (TI) rate, durability of response, and disease modification. In addition, side effects including cytopenia were manageable and reversible with dose modifications. This interview took place at the 28th Congress of the European Hematology Association (EHA) 2023 in Frankfurt, Germany.

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Disclosures

BMS, AbbVie, Takeda, Novartis, Aprea, Amgen, Otsuka, Gilead, Kura, Loxo Oncology, Geron, Mendus, Tyme: Consultancy, Honoraria, Membership on an entity’s Board of Directors or advisory committees.