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SOHO 2024 | Progress in the categorization and treatment of LR-MDS

Valeria Santini, MD, University of Florence, Florence, Italy, discusses the categorization system of lower-risk myelodysplastic syndromes (LR-MDS), stating that IPSS-M allows the best patient selection and therapy optimization. She mentions several agents that could treat LR-MDS, including erythropoiesis-stimulating agents (ESAs) and luspatercept, with a particular emphasis on the early use of lenalidomide to delay transfusion dependence. Additionally, Prof. Santini mentions the newly approved imetelstat, which can induce transfusion independence for longer than a year. This interview took place at the Twelfth Annual Meeting of the Society of Hematologic Oncology (SOHO 2024) congress in Houston, TX.

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