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ASH 2022 | Outcomes of patients with DLBCL who relapse early following R-ICE chemoimmunotherapy

Paolo Caimi, MD, Cleveland Clinic, Cleveland, OH, shares insights into the results of a study investigating the characteristics and outcomes of relapsed/refractory (R/R) patients with diffuse large B-cell lymphoma (DLBCL) achieving complete remission (CR) after treatment with rituximab, ifosfamide, carboplatin, and etoposide (R-ICE) chemoimmunotherapy. The study showed that whilst the majority of patients who relapsed early following R-ICE had poor outcomes, a minority of patients remained chemosensitive and were able to achieve long-term disease control, in particular if they proceeded to autologous transplantation. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Bristol Myers Squibb: Membership on an entity’s Board of Directors or advisory committees; Genmab: Membership on an entity’s Board of Directors or advisory committees; Genentech: Membership on an entity’s Board of Directors or advisory committees; Takeda: Membership on an entity’s Board of Directors or advisory committees; MEI Pharma: Membership on an entity’s Board of Directors or advisory committees; ADC Therapeutics: Membership on an entity’s Board of Directors or advisory committees; Novartis: Membership on an entity’s Board of Directors or advisory committees; Kite Pharma: Membership on an entity’s Board of Directors or advisory committees.