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ISTH 2023 | Promising novel approaches for inhibitor suppression in hemophilia

In this video, Margaret Ragni, MD, MPH, University of Pittsburgh, Pittsburgh, PA, shares insights into promising therapies for patients with hemophilia who develop inhibitors. Prof. Ragni comments on a variety of novel approaches, including the use of supplemented carbohydrates to alter the gut microbiota, coupling of blood cells to suppress inhibitor formation, and suppression of HLA II antigens. This interview took place at the 31st Congress of the International Society on Thrombosis and Haemostasis (ISTH), held in Montréal, Canada.

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Disclosures

Consulting and research grants – BioMarin, Sanofi, Spark, Takeda; consulting for BeBio Inc. and for HEMAB, ICER; Serve on Advisory Bd FWGBD; Serve on Editorial Bd for Blood Advances.