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EHA 2024 | Preliminary results from arm D of the SEQUOIA study: zanubrutinib plus venetoclax in CLL

Paolo Ghia, MD, Vita-Salute San Raffaele University, Milan, Italy, presents findings from arm D of the SEQUOIA study (NCT03336333), which is investigating the combination of zanubrutinib with venetoclax in chronic lymphocytic leukemia (CLL). The study found that patients with high-risk del17p or TP53 mutations had an undetectable measurable residual disease (MRD) rate of 59% in the bone marrow, but longer follow-up is needed. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

Research Funding: BeiGene, BMS, Lilly/Loxo Oncology, AstraZeneca, Janssen, MSD, AbbVie, Roche; Consultancy: BeiGene, BMS, Lilly/Loxo Oncology, AstraZeneca, Janssen, MSD, AbbVie, Roche; Honoraria: BeiGene, BMS, Lilly/Loxo Oncology, AstraZeneca, Janssen, MSD, AbbVie, Roche.