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ERIC 2024 | The structure and function of BCRs in the biology of CLL
Francesco Forconi, MD, DM, PhD, FRCPath, University of Southampton, Southampton, UK, discusses the structure and function of B-cell receptors (BCRs) and their influence on the biology of chronic lymphocytic leukemia (CLL). He explains that single-cell analysis reveals CLL cells live in a dynamic state influenced by antigen engagement, which affects their survival and proliferation. This interview took place at the 2024 European Research Initiative on CLL (ERIC) Meeting in Barcelona, Spain.
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