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SOHO 2024 | Gilteritinib monotherapy vs combination therapy in R/R FLT3-mutated AML

Akhil Rajendra Kurup, MD, Princess Margaret Hospital, Toronto, Canada, discusses a retrospective study comparing gilteritinib monotherapy to gilteritinib-containing combination therapies for the treatment of relapsed/refractory (R/R) FLT3-mutated acute myeloid leukemia (AML). Treatment with a combination therapy resulted in a longer median overall survival (OS) and greater complete response (CR) rate, highlighting that combination therapies with gilteritinib are a superior strategy to gilteritinib alone when bridging patients with FLT3-mutated AML to transplant. This interview took place at the Twelfth Annual Meeting of the Society of Hematologic Oncology (SOHO 2024) congress in Houston, TX.

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