Panagiotis Baliakas, MD, PhD, from Uppsala University, Uppsala, Sweden, explains the reasons why cytogenetic analyses are seldom performed in clinical studies and diagnoses of chronic lymphocytic leukemia (CLL). He also notes a parallel study being conducted in the European research organization, ERIC, that is currently evaluating methodologies similar to cytogenetic analyses that may be able to replace them. This video was recorded at the International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2017 in New York, NY.