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ASH 2021 | PET2-assoicated outcomes in patients with DLBCL

Conflicting data exists on the association between positron emission tomography scans after 2 cycles of therapy (PET2) and survival rates in patients with diffuse large B-cell lymphoma (DLBCL) who progress after rituximab, doxorubicin, cyclophosphamide, vincristine, and prednisone (R-CHOP). Sanjal Desai, MBBS, Mayo Clinic, Rochester, MN, investigates the impact of PET2 on survival in patients with DLBCL. Patients from a Phase II trial (NCT00670358) and the Mayo Clinic Molecular Epidemiology Resource were included in the analysis. Patients who are PET2-postive were found to have inferior overall survival and progression-free survival rates. This interview took place at the 63rd ASH Annual Meeting and Exposition congress in Atlanta, GA.