Sylvain Garciaz, MD, Paoli-Calmettes Institute, Marseille, France, discusses a retrospective study comparing venetoclax (ven) plus azacitidine (aza) to azacitidine monotherapy in patients with acute myeloid leukemia (AML) in first relapse or refractory to intensive chemotherapy. The combination therapy resulted in an overall response rate (ORR) of 55% and a median survival of one year, compared to eight months for azacitidine alone. Multivariate analysis highlighted the factors predicting poorer overall survival (OS). This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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