Akshay Sharma, MBBS, St. Jude Children’s Research Hospital, Memphis, TN, shares the results of a study investigating the impact of cytogenetic abnormalities observed at diagnosis on the outcomes of pediatric patients with acute myeloid leukemia (AML) with poor-risk cytogenetic abnormalities following stem cell transplantation (SCT). The study reported that cytogenetic abnormalities at diagnosis are predictive of overall survival (OS) following SCT in pediatric patients. In addition, whilst monosomy 7/del7q or monosomy 5/del5q were found to confer a poor prognosis following HCT, 11q23 abnormality and other poor-risk abnormalities were associated with favorable outcomes after SCT. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.