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ASH 2025 | Is the biology of T-cell malignancies too complex for a single-agent immunotherapy approach?
Yumeng Zhang, MD, Moffitt Cancer Center, Tampa, FL, highlights the biological complexity of T-cell lymphomas and the limitations of single-agent approaches in aggressive subtypes, such as peripheral T-cell lymphoma (PTCL). She emphasizes the need for rational combination strategies that both reduce tumor burden and enhance antitumor immunity, noting that future progress will depend on identifying the optimal agents and timing for these combinations. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.
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