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EHA 2024 | The safety and efficacy of the Syk inhibitor sovleplenib in heavily pre-treated Hodgkin lymphoma

Paolo Strati, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, comments on a study investigating the safety and efficacy of sovleplenib, a spleen tyrosine kinase (Syk) inhibitor, in patients with heavily pre-treated Hodgkin lymphoma (HL) (NCT03779113). The safety profile was manageable, and the agent successfully induced durable complete remission (CR) and measurable residual disease (MRD) eradication in a proportion of patients. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

Consulting or Advisory Role: Genentech/Roche, ADC Therapeutics, TG Therapeutics, Kite, a Gilead company. Research Funding: AstraZeneca, ALX Oncology, Gilead Sciences. Travel, Accommodations, Expenses: SOBI.