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ASH 2022 | Outcomes of delaying CAR-T infusion after lymphodepleting chemotherapy in patients with LBCL

Paolo Strati, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses the results of a study investigating the effect of delaying CAR-T infusion after completion of lymphodepleting chemotherapy on the outcomes of patients with large B-cell lymphoma (LBCL). Dr Strati explains that the most common reason for delaying CAR-T infusion is infections. The study found that patients who had delayed infusion had a shorter progression-free survival (PFS). This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Hutchinson MediPharma: Consultancy; ADC Therapeutics: Consultancy, Research Funding; TG Therapeutics: Consultancy; Kite Gilead: Consultancy; Astrazeneca Acerta: Research Funding; ALX Oncology: Research Funding; Sobi: Research Funding; Roche Genentech: Consultancy.