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EHA 2025 | Targeting SLAMF6 upregulation in AML: development of a novel antibody

In this presentation, Carl Sandén, PhD, Lund University, Lund, Sweden, discusses the potential of targeting SLAMF6 as a novel mechanism to overcome immune evasion in acute myeloid leukemia (AML). Dr Sandén highlights that SLAMF6 upregulation is a common immune escape mechanism in AML, where it protects leukemia cells from immune cell-mediated killing. He then shares insights into an antibody being developed to target SLAMF6. This press briefing took place at the 30th Congress of the European Hematology Association (EHA) in Milan, Italy.

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