Academic history
Thomas Alexander is an Assistant Professor of Pediatrics at The University of North Carolina (UNC) at Chapel Hill, NC, and is the Co-Leader of the Pediatric Oncology Developmental Therapeutics and Pharmacology Program at UNC. He received his medical degree from the UNC at Chapel Hill School of Medicine and subsequently completed his residency in internal medicine/pediatrics at UNC Hospitals, Chapel Hill, NC. He then completed a fellowship in pediatric hematology/oncology at the University of Tennessee, Knoxville, TN.
Speaking on the genomics of acute leukemia
Dr Alexander’s research primarily focuses on combining cancer genomic sequencing with early phase clinical trials to enhance understanding of disease response dynamics and improve outcomes in childhood leukemia and other hematological malignancies. He is also developing a project to explore a novel sequencing platform for cancer diagnostics, specifically with the goal of improving diagnostic capabilities in low and middle income counties.
Dr Alexander is currently involved in several clinical trials on leukemias. Two such trials include in a Phase I trial investigating the safety and preliminary efficacy of venetoclax with navitoclax in patients with relapsed or refractory acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma, as well as a Phase I trial investigating the safety of panobinostat in patients with relapsed or refractory acute myeloid leukemia (AML).
