Thomas Evans is Director of the Institute of Cancer Sciences, Lead of the Glasgow Experimental Cancer Medicine Centre, and a Professor of Translational Cancer Research. Prof. Evans received his MBBS degree at St Bartholomew’s Hospital Medical School in London, UK, in 1984, and became a Clinical Lecturer in Medical Oncology at St George’s Hospital, London, UK, in 1991.
Speaking on pre-clinical and clinical development of novel anti-cancer agents
Prof. Evans’ recent research has focused on pancreatic cancer, with involvement in a clinical trial to make cancer cells more responsive to chemotherapy and radiotherapy and development of drugs that stop the spread of pancreatic cancer. In addition, he is involved in novel therapies for gastro-esophageal and hepato-biliary-pancreatic cancers and melanoma.
Prof. Evans is also increasing efforts to understand the molecular basis of cancer. Current molecularly-targeted therapies focus on reducing tumor size, which may not be the best parameter in determining response. He hopes to find a solution to this problem by developing new biomarkers of anti-tumor activity, and new laboratory models that can suitably evaluate drug candidates in future clinical trials.