Barbara Savoldo, MD, PhD, is both Assistant Director of the Immunotherapy Program at UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC and a Professor of Pediatric Hematology-Oncology at University of North Carolina School of Medicine, Chapel Hill, NC. Prof. Savoldo received her medical degree and undertook a hematology fellowship at the University of Parma, Parma, Italy. Following this, Prof. Savoldo completed her post-doctoral fellowship in translational research at the Center for Cell and Gene Therapy, Baylor College of Medicine in Houston, TX. Here, she also worked as an Instructor and Assistant Professor before transitioning into a tenured Associate Professor role.
Speaking on gene therapy and immunotherapy for acute lymphoblastic leukemia
Prof. Savoldo has most recently been interested in the re-direction of genetically modified T-cells to tumors by transgenic expression of alpha-betaTCRs or of chimeric tumor-specific receptors. This work is in the clinical trial stage as of now and aims to target hematological malignancies such as CD19+ leukemia/lymphomas and CD30+ Hodgkin lymphoma.