News

More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study. The study recommends that patients undergo a detailed cardiovascular history before being prescribed carfilzomib and then be monitored…
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How slow—or fast—older individuals with blood cancers are able to walk four meters (about 13 feet) holds critical information about their overall health and strongly predicts survival and unplanned hospital visits regardless of age, cancer or treatment type, or other…
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In a landmark study, scientists discovered what makes white blood cell counts spike in individuals who have high cholesterol, possibly leading to new therapies for heart disease. They looked at hypercholesterolemia, which is the type of high cholesterol that causes…
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Results of a Phase II clinical trial revealed that combination targeted therapy, consisting of rituximab, lenalidomide and ibrutinib (RLI), had an 84.6 percent overall response rate (ORR) and 38.5% complete response rate (CRR) when given prior to any chemotherapy for…
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The results of a new study suggest that patients living with HIV and one of a variety of potentially deadly cancers could be safely treated with the immunotherapy drug pembrolizumab, also known by its brand name, KEYTRUDA.
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Cancer researchers have discovered surprising new functions for a protein called MYC, a powerful oncogene that is estimated to drive the development of almost half a million new cancer cases in the US every year. The study shows that MYC…
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Researchers describe how prostate cancer cells develop the ability to mimic bone-forming cells called osteoblasts, enabling them to proliferate in the bone microenvironment.
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Researchers have identified a distinct subtype of primary central nervous system (PCNS) lymphoma that should be considered for surgical removal, suggesting a major shift in how this type of tumor is evaluated and managed.
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Meaningful studies are lacking for certain patient groups. Disease-specific registries could help close the data gap.
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Researchers have discovered a mechanism of drug resistance to Venetoclax®, also known as ABT-199, a BCL-2 targeting drug commonly used to treat chronic lymphocytic leukemia and acute myeloid leukemia. Their findings also suggest a possible co-treatment strategy to overcome this…
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Although classical Hodgkin's lymphoma is generally easily treatable today, many aspects of the disease still remain a mystery. A team has now identified an important signaling molecule in the biology of this lymphoma: LTA. It helps the cancer to grow…
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A subpopulation of bone cells releases factors that can halt the growth of breast cancer that's traveled to the bone, putting the cells in stasis.
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Hematologists are zeroing in on the escalating humanitarian crisis in southern Europe by assessing the burden of blood disorders among refugees and identifying strategies to facilitate more timely identification and treatment of refugees with sickle cell disease.
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Patients with advanced Hodgkin's lymphoma who have large tumors at the time of diagnosis may benefit from radiotherapy after chemotherapy even when all traces of the cancer appear to have gone.
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Researchers have identified what keeps some cancer cells dormant -- a finding which could uncover new approaches to preventing the spread of cancer.
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New findings about an aggressive form of leukemia could aid the development of novel drugs to treat the condition.
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Researchers tested to see if arsenic trioxide (ATO) was effective in combination with all-trans retinoic acid (ATRA) in in both the mouse model of acute myeloid leukemia (AML) and in human AML cells in the lab, and determined that the…
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Earlier this week, the Centers for Medicare and Medicaid Services (CMS) proposed to improve the reimbursement currently given to hospitals that provide chimeric antigen receptor T-cell (CAR-T) therapy to blood cancer patients as part of the FY 2020 Inpatient Prospective…
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Clinical study treating BPDCN with tagraxofusp led to first FDA approval for the disease.
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