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Breakthrough cellular genomics technology has allowed researchers to reveal genetic mutations causing rogue behavior in the cells that cause autoimmune disease.
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According to results from a Phase I/IIa trial, treatment with cord blood-derived chimeric antigen receptor (CAR) natural killer (NK)-cell therapy targeting CD19 resulted in clinical responses in a majority of patients with relapsed or refractory non-Hodgkin's lymphoma (NHL) and chronic…
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Researchers have determined that a mutation affecting the important process of RNA splicing can manipulate the 'quality control' in your cell. The resulting conditions characterize many deadly blood cancers.
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Conventional thinking is that bone regeneration is left to a small number of mighty cells called skeletal stem cells, which reside within larger groups of bone marrow stromal cells.
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Today, the American Society of Hematology (ASH) released new clinical practice guidelines on Sickle Cell Disease (SCD)-Related Transfusion Support. These guidelines are part of a series of five guidelines ASH is developing on SCD to provide updated treatment guidelines that…
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The American Society of Hematology is pleased to announce that Gabriela Hobbs, MD, of Massachusetts General Hospital, and Oluwatoyosi Onwuemene, MD, MS, of Duke University have been selected to participate in the American Society of Hematology-Harold Amos Medical Faculty Development…
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Researchers have discovered ways to boost CAR T-cell therapy.
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A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia (AML), one of the most common forms of blood cancer. The researchers will now launch a clinical study to test the new…
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A new study shows that cancer-causing MLL gene may also push pluripotent stem cells to make hematopoietic stem cells, a strong step in the decades-long effort to make personalizable, durable blood stem cells.
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A new study suggests that extremely rare, harmful genetic mutations present in healthy donors' stem cells -- though not causing health problems in the donors -- may be passed on to cancer patients receiving stem cell transplants, potentially creating health…
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There has been a measurable decline in serious heart conditions among adult survivors of childhood cancer since the 1970s, finds a new study.
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Responders who worked at the World Trade Center site after the attacks on Sept. 11, 2001, have an increased overall cancer incidence compared to the general population, particularly in thyroid cancer, prostate cancer, and, for the first time ever reported,…
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Studying mice, researchers have found a driver of bone loss related to cancer treatment. Radiation and chemotherapy can halt cell division in bone, which results in a stress response called senescence. This process is independent of hormones that affect bone…
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Stephanie Lee, MD, MPH, a highly regarded expert in graft-versus-host disease as well as blood and bone marrow diseases, will serve as president of the American Society of Hematology for a year-long term through December 2020.
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People with metabolic syndrome – a set of conditions including obesity, impaired glucose metabolism, elevated levels of fats and cholesterol in the blood, and high blood pressure – are more likely to experience recurrent blood clots, according to a new…
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A research team has reproduced and visualized the earliest developmental steps in human immune cell production in the laboratory and are now set to advance our understanding of childhood diseases like leukemia and autoimmune conditions.
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A new study provides convincing evidence that the use of peripherally inserted central catheters (PICCs) to administer medicine and draw blood in children is associated with a significantly increased risk of blood clots (known as venous thromboembolism or VTE) compared…
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Artificial intelligence can detect one of the most common forms of blood cancer - acute myeloid leukemia -- with high reliability. Researchers at the DZNE and the University of Bonn have now shown this in a proof-of-concept study. Their approach…
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ASH today announced the 39 recipients of its 2020 Scholar Awards. One of ASH’s most prestigious research award programs, the ASH Scholar Awards financially support fellows to junior faculty dedicated to careers in hematology research as they transition from training…
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On Monday, bipartisan leaders in the House and Senate reached an agreement on a $1.3 trillion federal spending deal for fiscal year 2020. The legislation package – which Congress is expected to pass and then submit to President Trump for…
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