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A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia (AML), one of the most common forms of blood cancer. The researchers will now launch a clinical study to test the new…
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A new study shows that cancer-causing MLL gene may also push pluripotent stem cells to make hematopoietic stem cells, a strong step in the decades-long effort to make personalizable, durable blood stem cells.
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A new study suggests that extremely rare, harmful genetic mutations present in healthy donors' stem cells -- though not causing health problems in the donors -- may be passed on to cancer patients receiving stem cell transplants, potentially creating health…
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There has been a measurable decline in serious heart conditions among adult survivors of childhood cancer since the 1970s, finds a new study.
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Responders who worked at the World Trade Center site after the attacks on Sept. 11, 2001, have an increased overall cancer incidence compared to the general population, particularly in thyroid cancer, prostate cancer, and, for the first time ever reported,…
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Studying mice, researchers have found a driver of bone loss related to cancer treatment. Radiation and chemotherapy can halt cell division in bone, which results in a stress response called senescence. This process is independent of hormones that affect bone…
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Stephanie Lee, MD, MPH, a highly regarded expert in graft-versus-host disease as well as blood and bone marrow diseases, will serve as president of the American Society of Hematology for a year-long term through December 2020.
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People with metabolic syndrome – a set of conditions including obesity, impaired glucose metabolism, elevated levels of fats and cholesterol in the blood, and high blood pressure – are more likely to experience recurrent blood clots, according to a new…
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A research team has reproduced and visualized the earliest developmental steps in human immune cell production in the laboratory and are now set to advance our understanding of childhood diseases like leukemia and autoimmune conditions.
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A new study provides convincing evidence that the use of peripherally inserted central catheters (PICCs) to administer medicine and draw blood in children is associated with a significantly increased risk of blood clots (known as venous thromboembolism or VTE) compared…
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Artificial intelligence can detect one of the most common forms of blood cancer - acute myeloid leukemia -- with high reliability. Researchers at the DZNE and the University of Bonn have now shown this in a proof-of-concept study. Their approach…
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ASH today announced the 39 recipients of its 2020 Scholar Awards. One of ASH’s most prestigious research award programs, the ASH Scholar Awards financially support fellows to junior faculty dedicated to careers in hematology research as they transition from training…
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On Monday, bipartisan leaders in the House and Senate reached an agreement on a $1.3 trillion federal spending deal for fiscal year 2020. The legislation package – which Congress is expected to pass and then submit to President Trump for…
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Patients with acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML) who are treated with anthracyclines are at a heightened risk of heart failure -- most often within one year of exposure to the chemotherapy treatment, according to a new…
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Patients with cold agglutinin disease (CAD) had improved hemoglobin levels, required fewer blood transfusions, and felt significantly less fatigued after receiving the experimental drug sutimlimab for 26 weeks in a phase III clinical trial.
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Adding daratumumab to carfilzomib and dexamethasone to treat patients with relapsed or refractory multiple myeloma led to a significant survival benefit, according to a study presented today during the 61st American Society of Hematology (ASH) Annual Meeting and Exposition in…
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Researchers have completed the first comprehensive analysis combining full genomic sequencing and gene expression profiles of more than 1,300 patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
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Using an investigational oral form of azacitidine therapy, CC-486, significantly improved overall survival in older patients with newly diagnosed acute myeloid leukemia (AML) who were in remission following standard induction chemotherapy with or without consolidation therapy, according to a phase…
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Three adult patients with sickle cell disease (SCD) are doing well after receiving an infusion of their own stem cells that had been genetically engineered to induce them to stop producing harmful “sickle” hemoglobin and start producing a healthy form…
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The American Society of Hematology and the American Society of Pediatric Hematology/Oncology today released a list on reducing unnecessary tests and procedures in the pediatric population.
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