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Gene Therapy

The future of CAR-T therapy in ALL

Acute lymphoblastic leukemia (ALL) is an aggressive and heterogeneous disease with a high mortality rate. However, several advances have been…

Date: 20th July 2022

An insight into novel targets in myeloma and mechanisms of resistance to PIs and IMiDs

Multiple myeloma has seen many advances in recent years, and novel targeted agents are transforming the field. Several immunotherapies, including…

Date: 15th July 2022

Impact of the COVID-19 pandemic on the EBMT & projects in the pipeline

The 48th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), which took place on 19-23 March…

Date: 3rd June 2022

CAR-T and lymphoma treatment in the UK

Lymphoma treatment has seen many recent advances, with CAR-T therapy being a game changer for patients. Several clinical trials investigating…

Date: 27th May 2022

Harnessing the power of immunotherapy in myeloma and amyloidosis

The myeloma treatment landscape has seen a lot of progress in the last few years, with several novel therapies emerging,…

Date: 20th May 2022

Genomics in the age of immuno-oncology

Immunotherapies are at the forefront of myeloma treatment and there are many questions remaining. Defining high-risk is important when making…

Date: 29th April 2022

ASH 2021: what did ASH 2021 mean for MDS?

With high rates of relapse in patients with myelodysplastic syndromes (MDS), there is a great unmet need for novel treatments…

Date: 18th March 2022

ASH 2021: the future of cell therapies in lymphoma

Cell therapies including chimeric antigen receptor (CAR) T-cell therapy represent novel treatments for patients with lymphoma, especially for those who…

Date: 25th February 2022

The Lymphoma Sessions: post-ASH 2021

The 63rd American Society of Hematology (ASH) annual meeting saw a plethora of updates in lymphoma. While most of them…

Date: 2nd February 2022

COSTEM: the role of alloHSCT in ALL

Over the past few years, the therapeutic landscape for acute lymphoblastic leukemia (ALL) has dramatically evolved, with the development of…

Date: 25th October 2021

IACH 2021: CAR-T in clinical practice

Currently, five chimeric antigen receptor T-cell (CAR-T) therapies are approved for the treatment of hematological malignancies including acute lymphoblastic leukemia,…

Date: 30th September 2021

CAR-T vs bispecifics: replacing ASCT in myeloma

Autologous stem cell transplantation (ASCT) has been the standard of care patients with multiple myeloma for the past three decades;…

Date: 17th September 2021