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Post-ASCO & EHA 2024 MPN Highlights

25 June 2024 | Virtual Meeting

Post-ASCO & EHA 2024 MPN Highlights

25 June 2024 | Virtual Meeting

Presentation summaries of key MPN abstracts from ASCO & EHA 2024 featuring panel discussions with leading experts

The Post-ASCO & EHA 2024 MPN Highlights was supported by GSK. Supporters have no influence over the production of content.

Novel treatments and treatment combinations for MPNs

Jean-Jacques  Kiladjian
JAK2V617F molecular response correlates with EFS in an early PV population
Jean-Jacques Kiladjian Saint-Louis Hospital & Paris Diderot University, Paris, France
Claire Harrison
RESTORE: Elritercept for MF and mitigating ruxolitinib-associated cytopenias
Claire Harrison Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom
Raajit Rampal
MANIFEST-2: pelabresib + ruxolitinib for JAKi treatment-naïve pts with MF
Raajit Rampal Memorial Sloan Kettering Cancer Center, New York City, NY, United States
Naveen  Pemmaraju
TRANSFORM-1: navitoclax + RUX vs. RUX + PBO in pts with untreated MF
Naveen Pemmaraju The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Alex Rampotas
A novel CAR-T cell therapy against calreticulin mutant neoplasms
Alex Rampotas University College London Cancer Institute, London, United Kingdom
Session 1 panel discussion

Updates in outcomes following HSCT in myelofibrosis

Kristin Rathje
Comparing pre-tranplant, peri-transplant and no JAKi on outcomes after HSCT for MF
Kristin Rathje University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Haris Ali
Hypomethylating agents are effective in treating relapsed MF post allo-HSCT
Haris Ali City of Hope, Duarte, CA, United States
Session 2 panel discussion

Current evidence for long-term & real-world outcomes

Nieves Garcia-Gisbert
Clinical & molecular characterisation of pts w. low JAK2V617F allele burden
Nieves Garcia-Gisbert Hospital del Mar Research Institute, Barcelona, Spain
Valentin Garcia Gutiérrez
Momelotinib as an alternative therapy to other JAKi in MF pts with anemia
Valentin Garcia Gutiérrez Ramón y Cajal Hospital, Madrid, Spain
John  Mascarenhas
RW treatment patterns & outcomes in pts w. MF treated w. pacritinib in USA
John Mascarenhas Icahn School of Medicine at Mount Sinai, New York City, NY, United States
Session 3 panel discussion

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