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Miami Myeloma MRD 2025

11 April 2025 | Miami, FL & virtual

Miami Myeloma MRD 2025

11 April 2025 | Miami, FL & virtual
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The Miami Myeloma MRD 2025 Meeting was hosted by the Myeloma Institute at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, in collaboration with the Multiple Myeloma Research Foundation (MMRF), International Myeloma Foundation (IMF), HealthTree Foundation for Multiple Myeloma and World Health Communications, with VJHemOnc as official media partner.

The Miami Myeloma 2025 Workshop was supported by AstraZeneca, GSK, Abbvie, Adaptive, Johnson & Johnson, Pfizer, Sanofi, Bristol Myers Squibb and Sebia. Supporters have no influence on the production of content.

The workshop was held on April 11, 2025, and brought together leading experts in multiple myeloma to discuss the use of measurable residual disease (MRD) in clinical and trial settings, furthering our understanding of recent advances, and encouraging interactive discussion.

MRD as an early endpoint for accelerated approval

Ola Landgren
EVIDENCE meta-analysis
Ola Landgren Sylvester Comprehensive Cancer Center, Miami, FL, United States
Dickran Kazandjian
Review of the ODAC regulatory perspectives on MRD in myeloma
Dickran Kazandjian Sylvester Comprehensive Cancer Center, Miami, FL, United States

The evolution of MRD negativity in newly diagnosed myeloma

Marc  Raab
GMMG-HD7 and PERSEUS trials
Marc Raab Heidelberg Myeloma Center, Heidelberg, Germany
Katja  Weisel
CONCEPT trial
Katja Weisel University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Content coming soon
IMROZ and CEPHEUS trials
Content coming soon
Xavier  Leleu
BENEFIT trial
Xavier Leleu Poitiers University Hospital, Poitiers, France
Content coming soon

MRD driven clinical trials

Amrita Krishnan
DRAMMATIC trial
Amrita Krishnan City of Hope Medical Center
Fredrik Schjesvold
The REMNANT trial – treating MRD relapse
Fredrik Schjesvold Oslo University Hospital, Oslo, Norway
Content coming soon
EMN20 trial
Content coming soon

The use of MRD in MMRFs clinical program

Hearn Jay Cho
Horizon clinical program
Hearn Jay Cho Icahn School of Medicine at Mount Sinai Hospital, New York City, NY, United States
Cindy Varga
Horizon One and MRD in relapsed/refractory myeloma
Cindy Varga Atrium Health, Charlotte, NC, United States
Sham Mailankody
Horizon Two and MRD in high-risk newly diagnosed multiple myeloma
Sham Mailankody Memorial Sloan Kettering Cancer Centre, New York City, NY, United States

Emerging MRD technologies

Malin Hultcrantz
ClonoSEQ MRD assay
Malin Hultcrantz Memorial Sloan Kettering Cancer Center, New York City, NY, United States
Hans Lee
Circulating tumor cells
Hans Lee The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Cell-free DNA
Dan Landau
Content coming soon
Hitomi Hosoya
ctDNA-MRD as an early endpoint in myeloma and next steps
Hitomi Hosoya Stanford Medicine, Stanford, CA, United States
Content coming soon
Kenneth Shain
V(D)J sequencing
Kenneth Shain Moffitt Cancer Center, Tampa, FL, United States
Katie Thoren
Clonotypic peptides
Katie Thoren University of Miami, Miami, FL, United States
MALDI TOF MS
Content coming soon
David Coffey
Multi-omics DNA/RNA/protein
David Coffey Sylvester Comprehensive Cancer Center, Miami, FL, United States
Content coming soon