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The 3rd International Workshop on Myelodysplastic Syndromes & Myeloproliferative Neoplasms (iwMDS & iwMPN) took place on 27–29 June 2025, in Lisbon, Portugal. At this event, the world’s leading clinical researchers in MDS & MPNs shared their perspectives on how to place the evolving understanding of these hematological malignancies in a clinical context to optimize clinical care.   The iwMDS and MPN 2025 Workshop was supported by Agios, Faron, Genentech, Geron, Sumitomo Pharma, Bristol Myers Squibb, GSK and Kartos Therapeutics. Supporters have no influence over the production of content.

iwMPN 2025

The 3rd International Workshop on MDS & MPNs
27–29 June 2025 | Lisbon, Portugal

iwMPN 2025

The 3rd International Workshop on MDS & MPNs
27–29 June 2025 | Lisbon, Portugal
The 3rd International Workshop on Myelodysplastic Syndromes & Myeloproliferative Neoplasms (iwMDS & iwMPN) took place on 27–29 June 2025, in Lisbon, Portugal. At this event, the world’s leading clinical researchers in MDS & MPNs shared their perspectives on how to place the evolving understanding of these hematological malignancies in a clinical context to optimize clinical care.   The iwMDS and MPN 2025 Workshop was supported by Agios, Faron, Genentech, Geron, Sumitomo Pharma, Bristol Myers Squibb, GSK and Kartos Therapeutics. Supporters have no influence over the production of content.

 Challenging and uncommon scenarios in MPN (part I)

Marta Sobas
Young patients
Marta Sobas Wroclaw Medical University, Wrocław, Poland
Susan Robinson
Pregnancy in MPN
Susan Robinson Guy's and St Thomas' NHS Foundation Trust , London, United Kingdom
Jon Lambert
Skin cancer
Jon Lambert UCL Cancer Institute, London, United Kingdom

 

Challenging and uncommon scenarios in MPN (part II)

Nicola  Polverelli
Transplantation for rare MPN
Nicola Polverelli IRCCS Policlinico San Matteo Foundation, Pavia , Italy

 

 Novel approaches to upfront management of MF (part I)

Alessandro Vannucchi
Classification and risk stratification
Alessandro Vannucchi University of Florence, Florence, Italy
Lucia Masarova
Relevance of cytopenias in MF for therapeutic decisions
Lucia Masarova The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Prithviraj Bose
When should a low-risk patient be treated and with what?
Prithviraj Bose The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Donal McLornan
What is a suboptimal responder?
Donal McLornan University College Hospital, London, United Kingdom

 

Novel approaches to upfront management of MF (part II)

Claire Harrison
Selinexor
Claire Harrison Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom
Prithviraj Bose
Updates on JAK inhibitors & JAKi-naïve studies
Prithviraj Bose The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Adam Mead
INCB057643 in Myelofibrosis & Myeloid Neoplasms
Adam Mead University of Oxford, Oxford, United Kingdom
Haifa Kathrin Al-Ali
Navtemadlin
Haifa Kathrin Al-Ali Martin Luther University of Halle-Wittenberg, Halle, Germany

 

Updates on new therapies (part I)

Jan Bewersdorf
Interferon
Jan Bewersdorf Yale Cancer Center, New Haven, CT, United States
Alessandro Vannucchi
Imetelstat
Alessandro Vannucchi University of Florence, Florence, Italy
Firas El Chaer
Nuvisertib
Firas El Chaer University of Virginia, Charlottesville, VA, United States
Claire Harrison
Elritercept
Claire Harrison Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom
Abdulraheem Yacoub
Tagraxofusp in MF
Abdulraheem Yacoub University of Kansas Medical Center, Kansas City, KS, United States

 

Updates on new therapies (part II)

Marina Kremyanskaya
Updates with hepicidin targets in PV
Marina Kremyanskaya Icahn School of Medicine at Mount Sinai, New York City, NY, United States
Shahram Kordasti
Targeting inflammation – lessons from MDS
Shahram Kordasti King’s College London, London, United Kingdom

 

Novel thoughts on blastic phase and transplantation

Adam Mead
Diagnosis and risk stratification of AP and BP
Adam Mead University of Oxford, Oxford, United Kingdom
Donal McLornan
Options for management of accelerated and blast phase: should they be treated in the same way and how should we incorporate BMT?
Donal McLornan University College Hospital, London, United Kingdom
Juan Carlos Hernández-Boluda
Transplant for MF
Juan Carlos Hernández-Boluda University Hospital, Valencia, Spain