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iwCAR-T 2023

The 5th International Workshop on CAR-T
14–16 April 2023 | Scottsdale, AZ

iwCAR-T 2023

The 5th International Workshop on CAR-T
14–16 April 2023 | Scottsdale, AZ

Explore presentations by leading experts from iwCAR-T 2023 below. Click here to view roundtable discussions.

Session 1: Current challenges

Marco Davila
Suppression mechanisms of CAR‐T cells
Marco Davila Roswell Park, Buffalo, NY, United States
Evan Weber
Enforcing memory programs to enhance CAR‐T persistence
Evan Weber Children's Hospital of Philadelphia, Philadelphia, PA, United States
Filip Ionescu
Cladribine & cyclophosphamide lymphodepletion
Filip Ionescu Moffitt Cancer Center, Tampa, FL, United States
Michael Green
Single cell analysis of CAR-T response and toxicity
Michael Green MD Anderson Cancer Center, Houston, TX, United States

Session 2: Toxicity

Matthew Frigault
CRS/ICANS prophylaxis attempts
Matthew Frigault Massachusetts General Hospital, Boston, MA, United States
Bianca  Santomasso
Update on management of neuro‐toxicities/CRS in CAR‐T
Bianca Santomasso Memorial Sloan Kettering Cancer Centre, New York City, NY, United States

Session 3: CAR‐T in ALL

Bijal Shah
ZUMA‐3 – brexucabtagene autoleucel for adult ALL
Bijal Shah H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
Claire Roddie
CD19‐targeted CAR T‐cell in R/R B‐cell ALL/Auto
Claire Roddie University College London, London, United Kingdom
Nirav Niranjan Shah
Bispecific LV20.19 and trispecific duo CAR20.19.22
Nirav Niranjan Shah Medical College of Wisconsin, Milwaukee, WI, United States
Maksim Mamonkin
CAR‐T for T‐ALL
Maksim Mamonkin Baylor College of Medicine, Houston, TX, United States

Session 4: CAR‐T in AML

Sebastian Kobold
Single‐cell analysis to develop new CAR therapies
Sebastian Kobold Ludwig Maximilian University, Munich, Germany
David Sallman
Outcomes in early‐phase CAR‐T clinical trials
David Sallman H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
Roman Shapiro
NK cell‐based immunotherapy
Roman Shapiro Dana-Farber Cancer Institute, Boston, MA, United States
Marion Subklewe
Updates on bispecifics
Marion Subklewe LMU Hospital Munich, Munich, Germany

Session 5: CAR‐T in lymphoma

Michael  Jain
Brexucabtagene autoleucel in R/R MCL
Michael Jain H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
Caron Jacobson
CARs for primary CNS lymphoma
Caron Jacobson Dana-Farber Cancer Institute, Boston, MA, United States
David Miklos
Alternative targets in lymphoma (CD22, ROR1)
David Miklos Stanford University, Stanford, CA, United States
Jeremy Abramson
Liso‐cel for the treatment of B‐cell lymphoma
Jeremy Abramson Massachusetts General Hospital Cancer Center, Boston, MA, United States
Loretta Nastoupil
CRISPR‐edited allogeneic anti‐CD19 CAR-T for for R/R B‐cell NHL
Loretta Nastoupil The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Mazyar Shadman
Bispecifics in DLBCL
Mazyar Shadman Fred Hutchinson Cancer Research Center, Seattle, WA, United States
Tycel Phillips
Bispecific treatments in FL and MCL
Tycel Phillips City of Hope, CA, United States

Session 6: Improving vein‐to‐vein time

Valentín Ortiz-Maldonado
Varnimcabtagene autoleucel for R/R B‐cell malignancies
Valentín Ortiz-Maldonado Hospital Clínic de Barcelona, Barcelona, Spain
Matthew Frigault
Challenges and approaches for rapid manufacturing
Matthew Frigault Massachusetts General Hospital, Boston, MA, United States

Keynote lecture

Renier Bretjens
Driving CAR T‐cells forward
Renier Bretjens Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States

Session 7: CAR‐T in multiple myeloma

Doris Hansen
Updates from the Myeloma CAR‐T Consortium:
Doris Hansen H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
Krina Patel
CAR‐T therapy work for high‐risk multiple myeloma patients
Krina Patel The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Rafael Fonseca
BCMA and non‐BCMA bispecific antibodies
Rafael Fonseca Mayo Clinic, Phoenix, AZ, United States
Nizar Bahlis
Mechanisms of resistance to BCMA‐targeted therapy
Nizar Bahlis Arnie Charbonneau Cancer Institute, Calgary, Canada
Sham Mailankody
AlloCART – will they be the solution to access in myeloma?
Sham Mailankody Memorial Sloan Kettering Cancer Centre, New York City, NY, United States
Eric Smith
GPRC5D CAR‐T in myeloma
Eric Smith Dana-Farber Cancer Institute, Boston, MA, United States

Session 8: CAR‐T in CLL

Joseph Melenhorst
Immune resistance in CLL
Joseph Melenhorst Cleveland Clinic, Cleveland, OH, United States
Tanya  Siddiqi
Update on TRANSCEND – liso‐cel in CLL/SLL
Tanya Siddiqi City of Hope, Duarte, CA, United States
Saar  Gill
CART‐19 with ibrutinib for the treatment of CLL
Saar Gill Perelman School of Medicine, Philadelphia, PA, United States

The continued success of the iwCAR-T meeting is in no small part due to the ongoing funding of supporters, allowing a unique opportunity for clinicians to be brought together to facilitate interactive and stimulating debates to help improve patient outcomes.
For more information about supporting future meetings and activities, please contact us here.

iwCAR-T 2023 was supported by: