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Per Ljungman, MD, PhD, Karolinska University Hospital, Solna, Sweden, discusses the management of HHV-6 infection in patients with hematological malignancies after hematopoietic stem cell transplantation (HSCT). This interview took place at the 5th International Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) 2019, held in Berlin, Germany.