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EHA 2026 | Insights into a study validating the ICC hierarchical classification in secondary AML

Maria Teresa Voso, MD, University Tor Vergata, Rome, Italy, shares insights from a study validating the International Consensus Classification (ICC) in secondary acute myeloid leukemia (AML). Dr Voso highlights that the genetic background, including cytogenetics and myelodysplasia-related mutations, is the major determinant of patient prognosis and identifies two distinct subgroups of myelodysplastic syndromes (MDS)-AML with different mutation patterns, confirming that stratification and treatment should follow genetics rather than prior patient history. This interview took place at the 31st Congress of the European Hematology Association (EHA) in Stockholm, Sweden.

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