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EHA 2026 | Age and cytogenetics influence prognostic value of copy number profiles in B-cell ALL

Anthony Moorman, PhD, Newcastle University, Newcastle, UK, discusses findings from a large HARMONY Alliance analysis exploring how age and cytogenetic risk influence the prognostic value of copy number alteration profiles in B-cell acute lymphoblastic leukemia (ALL). Prof. Moorman highlights how biomarkers derived from pediatric ALL are often less predictive in adult disease, underscoring the need for age-specific risk models and more comprehensive approaches to risk stratification beyond single biomarkers. This interview took place at the 31st Congress of the European Hematology Association (EHA) in Stockholm, Sweden.

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