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EHA 2026 | Post-transplant FLT3 inhibitor maintenance in AML: evidence and practical considerations

Robert Negrin, MD, Stanford University, Stanford, CA, discusses the growing role of FLT3 inhibitor maintenance therapy following allogeneic stem cell transplantation in FLT3-mutated acute myeloid leukemia (AML). Prof. Negrin reviews the evidence supporting post-transplant maintenance, particularly with gilteritinib, and discusses key considerations including toxicity management, patient selection, treatment duration, and molecular monitoring using PCR-based assays to detect relapse risk. This interview took place at the 31st Congress of the European Hematology Association (EHA) in Stockholm, Sweden.

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