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EHA 2026 | EBMT analysis: alloSCT may overcome FLT3-ITD risk in CBFB::MYH11-positive AML

Arnon Nagler, MD, Chaim Sheba Medical Center, Tel-Aviv, Israel, discusses findings from an analysis by the European Group for Blood and Marrow Transplantation (EBMT) evaluating the prognostic impact of FLT3-ITD mutations in patients with CBFB::MYH11-positive acute myeloid leukemia (AML) undergoing allogeneic stem cell transplantation (alloSCT). Prof. Nagler highlights data suggesting that transplantation may overcome the adverse prognostic effect of FLT3 mutations in this favorable-risk AML subgroup. This interview took place at the 31st Congress of the European Hematology Association (EHA) in Stockholm, Sweden.

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