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ESH MPN 2026 | Current understanding of the biological mechanisms underlying disease progression in MPNs

Stephen Oh, MD, PhD, Washington University School of Medicine, St. Louis, MO, highlights biological mechanisms underlying disease progression in MPNs, including the progress in research evaluating the effects of JAK2, CALR, MPL, and high-risk mutations. He explains that these biological mechanisms are still not fully understood and emphasizes the need for further research. This interview took place at the ESH 11th Translational Research Conference on Myeloproliferative Neoplasms (ESH MPN 2026) in Estoril, Portugal.

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