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ASH 2025 | Fatigue, Hb, & inflammatory markers in patients with wAIHA treated with rilzabrutinib in LUMINA2

In this video, David Kuter, MD, Massachusetts General Hospital, Boston, MA, discusses an analysis of data from the LUMINA2 study (NCT05002777), which investigated the use of rilzabrutinib, a BTK inhibitor, for the treatment of warm autoimmune hemolytic anemia (wAIHA). Prof. Kuter highlights that a significant hemoglobin (Hb) response was observed in over half of patients treated, with increases in Hb and declines in inflammatory markers correlating with subsequent improvements in fatigue scores. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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