Joshua Richter, MD, of Mount Sinai Medical Center, New York, NY, gives us his take on the key highlights in multiple myeloma (MM) from the American Society of Hematology (ASH) 2018 Annual Meeting and Exposition in San Diego, CA. Dr Richter discusses the up-and-coming new tools being investigated in clinical trials, and also reveals the use of old tools in novel ways, notably in the MAIA study (NCT02252172).