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iwNHL 2017 | Side effects of novel PI3K inhibitors

Nathan Fowler • 8 Sep 2017

Nathan Fowler, MD, from the University of Texas MD Anderson Cancer Center, Houston, TX, discusses side effects of PI3K inhibitors at the 2017 International Workshop in Non-Hodgkin Lymphoma (iwNHL) in Vancouver, BC, Canada. Transaminitis is where transaminases are elevated in the liver. This usually occurs at the start of treatment, and has been found to go away once stopping and restarting treatment. Other side effects include inflammatory conditions, such as colitis and pneumonitis. It is recommended that patients who present with these side effects stop treatment, and undergo an infectious workup.