In this video, we hear Mohamad Mohty, MD, PhD, Saint-Antoine Hospital, Paris, France, Jesús San Miguel, MD, PhD, University of Navarra, Pamplona, Spain and Graham Jackson, MBBS, FRCP, FRCPath, MD, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK discuss some of the highlights from day 2 at COMy 2022. This interview took place at the 8th World Congress on Controversies in Multiple Myeloma (COMy) 2022, held in Paris, France.