Andrew Wei, MBBS, PhD, Alfred Hospital and Monash University, Melbourne, Australia, covers the phase 1b trial (NCT02942290) of venetoclax in combination with azacitidine in treatment-naïve patients with higher-risk myelodysplastic syndrome (MDS). This revealed a tolerable safety profile and promising efficacy. This interview was recorded at the American Society of Hematology (ASH) 2019 Annual Meeting and Exposition in Orlando, FL.