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EBMT 2023 | Weighing up the pros and cons of CAR-T therapy and bispecific antibodies in R/R DLBCL

Anna Sureda, MD, PhD, Catalan Institute of Oncology, Duran I Reynals Hospital, Barcelona, Spain, compares benefits and drawbacks of CAR-T therapy and bispecific antibodies (BsAbs) in the context of relapsed/refractory diffuse large b-cell lymphoma (R/R DLBCL). Dr Sureda highlights the greater amount of follow-up data on CAR-T therapy, as well as the convenience of a ‘one-shot treatment’ while also acknowledging the more optimal toxicity profile, and enhanced accessibility of BsAbs. This interview took place at the 49th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT) held in Paris, France.

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Disclosures

Takeda: Consultancy, Honoraria, Research Funding, Speakers Bureau; BMS/Celgene: Consultancy, Honoraria, Research Funding; MSD: Consultancy, Honoraria; Kite: Consultancy, Honoraria; Novartis: Consultancy, Honoraria; Jannsen: Consultancy, Honoraria; Sanofi: Consultancy, Honoraria; GenMab: Consultancy, Honoraria; Pierre Fabre: Consultancy, Honoraria; Astra Zeneca: Consultancy, Honoraria.