Peter Bader, MD from the University Hospital Frankfurt, Frankfurt, Germany discusses the gains in transplantation in children and adolescents today at the 2016 EBMT International Transplant Course (EBMT-ITC) in Barcelona, Spain. Acting as Chair of the EBMT Paediatric Disease Working Party, Dr Bader outlines that as a result of better understanding of donor selection, conditioning regiments and post-transplantation care, 70-80% of children and adolescents are expected to survive allogeneic transplantation.