William Wierda, MD, PhD, from the MD Anderson Cancer Center, Houston, TX, provides us with an overview as to how physicians can provide help and information towards their patients about their cancer and explains how doctors differ in their approach and patients differ in how well-informed they wish to be. As detailed by Prof. Wierda, it is crucial to maintain a transparency between doctors and their patients to provide optimal cancer care. This video was recorded at the International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2017 in New York, NY.