Xavier Leleu, MD, PhD, from the Poitiers University Hospital, Poitiers, France, gives an overview of current clinical trials in multiple myeloma at the 2017 World Congress on Controversies in Multiple Myeloma (COMy) in Paris, France. He explains that the majority of clinical trials are assessing different combination therapies, either as induction, consolidation or maintenance therapy. Dr Leleu also speaks about response-adjusted clinical trials, where dosage is adjusted depending on depth of response.