Jan Geissler, Co-founder of the CML Advocates Network, introduces new European programs and initiatives relevant to hematology. He describes how he and other patient advocates will be involved in European Reference Networks (ERNs) set up by the European Commission (EC) and member states, whose aim is to drive clinical excellence in rare diseases, with ERN topics including rare cancers, hematology and pediatric cancers. An additional initiative is HARMONY, from the Innovative Medicines Initiative (IMI), which will use big data and complex analysis to optimize care and treatment in hematologic malignancies, in which patients will be deeply involved, and which he will be helping to coordinate.